Zambiri zoyambira
Dzina lazogulitsa | Catalogi | Mtundu | Host/Source | Kugwiritsa ntchito | Mapulogalamu | Epitope | COA |
HEV Antigen | HEV Antigen | Antigen | E.coli | Jambulani | CMIA, WB | / | Tsitsani |
HEV Antigen | BMIHEV012 | Antigen | E.coli | Conjugate | CMIA, WB | / | Tsitsani |
HEV Antigen | BMIHEV021 | Antigen | E.coli | Jambulani | CMIA, WB | / | Tsitsani |
HEV Antigen | BMIHEV022 | Antigen | E.coli | Conjugate | CMIA, WB | / | Tsitsani |
Kufala kwa matenda a chiwindi E (makamaka kudzera ndowe m`kamwa njira) ndi matenda mawonetseredwe (recessive matenda, pachimake chiwindi, palibe matenda a chiwindi, etc.) ndi ofanana ndi a chiwindi A. Kuchuluka kwa chiwindi E ndi mkulu achinyamata ndi akuluakulu a zaka 15-39 zaka.Hepatitis E ndi matenda odziletsa okha.HEV ilibenso Direct pathological effect (CPE) pa hepatocytes.Thupi limatha kukhala ndi chitetezo chamthupi pambuyo pa matenda, koma silikhazikika mokwanira.Pali katemera wa hepatitis E, ndipo njira zopewera matenda a chiwindi E makamaka ndikudula njira yopatsira chimbudzi m'kamwa.
HEV imatulutsidwa ndi ndowe za odwala, imafalikira kudzera m'moyo watsiku ndi tsiku, ndipo imatha kufalitsidwa kapena kufalikira kwa mliri woyambitsidwa ndi chakudya ndi madzi oipitsidwa.Kuchuluka kwa zochitika nthawi zambiri kumakhala m'nyengo yamvula kapena pambuyo pa kusefukira kwa madzi.Nthawi yoyamwitsa ndi masabata a 2-11, pafupifupi masabata asanu ndi limodzi.Ambiri mwa odwala omwe ali ndi matenda a chiwindi a chiwindi, nthawi zambiri amadziletsa okha, ndipo samakula kukhala HEV.Amakonda kwambiri achinyamata, opitilira 65% omwe amapezeka azaka zapakati pa 16 mpaka 19, ndipo ana amakhala ndi matenda ocheperako.
Mlandu wa imfa ya akuluakulu ndi apamwamba kuposa a chiwindi A, makamaka kwa amayi apakati omwe akudwala matenda a chiwindi E, ndi imfa mlingo wa matenda m'miyezi itatu yapitayo wa mimba ndi 20%.
Pambuyo pa matenda a HEV, imatha kupanga chitetezo chamthupi kuteteza HEV kuyambiranso kwa mtundu womwewo kapena mitundu ina.Zanenedwa kuti anti HEV antibody mu seramu ya odwala ambiri pambuyo pochira amakhala zaka 4-14.
Kuti mudziwe zoyesera, tinthu tating'onoting'ono ta virus titha kupezeka mu ndowe ndi maikulosikopu yama elekitironi, HEV RNA mu ndowe ya bile imatha kuzindikirika ndi RT-PCR, ndipo ma anti HEV IgM ndi IgG mu seramu amatha kuzindikirika ndi ELISA pogwiritsa ntchito recombinant HEV glutathione S-transferase fusion protein ngati antigen.
Kapewedwe ka matenda a chiwindi E ndi chimodzimodzi ndi a chiwindi B. Ma immunoglobulins wamba sagwira ntchito pakatemera wadzidzidzi.