CHIDULE NDI KUTANTHAUZA MAYESERO
Helicobacter pylori amagwirizana ndi zosiyanasiyana m`mimba matenda kuphatikizapo sanali chilonda dyspepsia, duodenal ndi chapamimba zilonda ndi yogwira, aakulu gastritis.Kuchuluka kwa matenda a H. pylori kumatha kupitilira 90% mwa odwala omwe ali ndi zizindikiro za matenda am'mimba.Kafukufuku waposachedwapa akuwonetsa mgwirizano wa matenda a H. pylori ndi khansa ya m'mimba.
pylori amatha kupatsirana kudzera mukudya chakudya kapena madzi omwe ali ndi ndowe.Mankhwala opha tizilombo ophatikizana ndi mankhwala a bismuth asonyezedwa kuti ndi othandiza pochiza matenda a H. Pylori..H.pylori pakali pano amazindikiridwa ndi njira zoyesera zoyeserera zotengera endoscopy ndi biopsy (ie histology, chikhalidwe) kapena njira zoyezera zosasokoneza monga kuyesa kwa urea kupuma (UBT), kuyesa kwa serologic antibody ndi kuyesa kwa antigen.UBT imafuna zida za labu zokwera mtengo komanso kugwiritsa ntchito makina opangira ma radioactive.Kuyesa kwa ma antibody a serologic sikusiyanitsa pakati pa matenda omwe akugwira ntchito pano komanso kuwonekera kapena matenda omwe adachiritsidwa.Mayeso a antigen a chopondapo amazindikira antigen yomwe ilipo mu ndowe, zomwe zikuwonetsa matenda a H. pylori.Ikhoza kugwiritsidwanso ntchito kuyang'anira momwe chithandizo chikuyendera komanso kuyambiranso kwa matenda.Mayeso a H. pylori Ag Rapid amagwiritsa ntchito golide wa colloidal conjugated monoclonal anti-H.pylori antibody ndi wina monoclonal anti-H.pylori antibody kuti azindikire mwachindunji ma antigen a H. pylori omwe ali m'chimbudzi cha wodwala yemwe ali ndi kachilombo.Mayesowa ndi osavuta kugwiritsa ntchito, olondola, ndipo zotsatira zake zimapezeka mkati mwa mphindi 15.
MFUNDO
Mayeso a H. pylori Ag Rapid ndi masangweji lateral flow chromatographic immunoassay.Mzere woyeserera uli ndi: 1) pad yamtundu wa burgundy conjugate yokhala ndi monoclonal anti-H.pylori antibody yolumikizidwa ndi golidi wa colloidal (anti-Hp conjugates) ndi 2) mzere wa membrane wa nitrocellulose wokhala ndi mzere woyesera (T mzere) ndi mzere wowongolera (C mzere).Mzere wa T umakutidwa kale ndi anti-H wina wa monoclonal.pylori antibody, ndipo C line idakutidwa kale ndi anti-mbewa IgG antibody.
Pamene chiwerengero chokwanira cha chimbudzi chochotsedwa chikaperekedwa mu chitsime cha kaseti yoyesera, chitsanzocho chimasuntha ndi capillary action kudutsa kaseti.Ma antigen a H. pylori, ngati alipo mu chitsanzocho, adzamangiriza ku anti-Hp conjugates. The immunocomplex kenaka imagwidwa pa nembanemba ndi anti-antibody yophimbidwa kale yomwe imapanga burgundy mtundu wa T mzere, kusonyeza zotsatira zabwino za mayeso a H. pylori.Kusowa kwa mzere wa T kumasonyeza kuti chiwerengero cha ma antigen a H. pylori mu chitsanzocho chili pansi pa mlingo wodziwika, kusonyeza zotsatira za mayeso a H. pylori. immunocomplex ya mbuzi anti-mbewa IgG/mbewa IgG-golide conjugate mosasamala kanthu za kukula kwa mtundu pa mzere wa T.Ngati mzere wa C sunapangidwe, zotsatira zake zimakhala zosavomerezeka ndipo chitsanzocho chiyenera kuyesedwanso ndi chipangizo china.
