CHIDULE NDI KUTANTHAUZA MAYESERO
Matenda otchedwa lymphatic filariasis otchedwa Elephantiasis, omwe amayamba makamaka ndi W. bancrofti ndi B. malayi, amakhudza anthu pafupifupi 120 miliyoni m’mayiko 80.Matendawa amafalikira kwa anthu mwa kulumidwa ndi udzudzu womwe uli ndi kachilombo mkati mwake momwe tinthu tating'onoting'ono tomwe timayamwa kuchokera kwa munthu yemwe ali ndi kachilomboka timapanga mphutsi za gawo lachitatu.Nthawi zambiri, kukhudzana mobwerezabwereza ndi yaitali kukhudzana ndi kachilombo mphutsi chofunika kukhazikitsidwa kwa anthu matenda.
Kuzindikira kotsimikizika kwa parasitologic ndikuwonetsa ma microflariae mu zitsanzo zamagazi.Komabe, kuyesa kwa golide kumeneku kumakhala koletsedwa ndi kufunikira kwa kusonkhanitsa magazi usiku komanso kusowa kwa mphamvu zokwanira.Kuzindikira kwa ma antigen ozungulira kulipo pamalonda.Zothandiza zake ndizochepa kwa W. bancrofti.Kuphatikiza apo, microfilaremia ndi antigenemia zimayamba kuchokera miyezi kupita kuzaka pambuyo powonekera.
Kuzindikira ma antibodies kumapereka njira yodziwira matenda a filarial parasite.Kukhalapo kwa IgM ku ma antigen a parasite kumasonyeza kuti muli ndi kachilombo ka HIV, pamene IgG imafanana ndi matenda ochedwa kapena matenda apitalo.Kuphatikiza apo, kuzindikiritsa ma antigen osungidwa kumalola kuyesa kwa 'pan-filaria' kuti kugwire ntchito.Kugwiritsiridwa ntchito kwa mapuloteni ophatikizananso kumathetsa kusagwirizana ndi anthu omwe ali ndi matenda ena a parasitic.
Filariasis Ab Rapid Test imagwiritsa ntchito ma antigen osungidwa kuti azindikire Antibody ku W. bancrofti ndi B. malayi majeremusi popanda kuletsa kusonkhanitsa zitsanzo.
MFUNDO
Filariasis Ab Rapid Test ndi lateral flow chromatographic immunoassay.Kaseti yoyesera imakhala ndi: 1) pad yamtundu wa burgundy yokhala ndi antijeni ya Filariasis yolumikizana ndi golidi wa colloid (Filariasis conjugates) ndi kalulu IgG-golide conjugates, 2) chingwe cha nitrocellulose chokhala ndi bandi yoyesera (T band) ndi chowongolera. gulu (C gulu).T band idakutidwa kale ndi anti-conjugated Filariasis antigen, ndipo C band idakutidwa kale ndi anti-Rabbit IgG antibody.
Pamene chiwerengero chokwanira cha chitsanzo choyesera chaperekedwa mu chitsime cha kaseti yoyesera, chitsanzocho chimasuntha ndi capillary action kudutsa kaseti.AntiFilariasis Ab ngati alipo mu chitsanzo adzamanga kwa Filariasis conjugates.The immunocomplex ndiye amagwidwa pa nembanemba ndi antigen pre- TACHIMATA, kupanga burgundy mtundu T band, kusonyeza aFilariasis Ab zotsatira zabwino mayeso.Kusakhalapo kwa T band kukuwonetsa zotsatira zoyipa.Mayesowa ali ndi chowongolera chamkati (C band) chomwe chimayenera kuwonetsa gulu lamtundu wa burgundy la immunocomplex la anti-rabbit IgG/rabbit IgG-gold conjugate mosasamala kanthu za kukula kwa mtundu pa T band.Apo ayi, zotsatira zake ndizolakwika ndipo chitsanzocho chiyenera kuyesedwanso ndi chipangizo china.
